Structure Function Relationships of Human Pathogenic Viruses

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Structure-Function Relationships of Human Pathogenic Viruses

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Structure Function Relationships of Human Pathogenic Viruses

Enter pincode. Usually delivered in days? Structure-Function Relationships of Human Pathogenic Viruses provides information on the mechanisms by which viruses enter the cell, replicate, package their DNA into capsids and mature into new virions.

The relation between structural features and the pathogenicity and oncogenicity of some of the most relevant human viral pathogens are demonstrated and the acquisition of defense mechanisms through virus-host interactions are presented. In contrast to textbooks, this volume combines timely research data to provide a holistic view of viral pathogenesis. Approaches in nanomedicine and nanopharmacology in which various biophysical techniques such as NMR Nuclear Magnetic Resonance , AFM Atomic Force Microscopy , SPR Surface Plasmon Resonance and X-ray crystallography can be combined with biochemical and cell-biological methods will lead to improved antimicrobial peptides by this rational drug design approach.

Such a strategy is extremely well suited to support clinical studies focussing on an effective fight against multiresistant pathogens. The data sets which are described here can be considered as universal for the design of various antimicrobial drugs against certain pathogens bacteria, viruses and fungi which cause severe diseases in humans and animals.

Furthermore, these insights are also helpful for progressing developments in the field of food conservation and food preservation. A detailed analysis of the structure-function relationships between antimicrobial peptides and contact molecules on pathogen surfaces at the sub-molecular level will lead to a higher degree of specificity of antimicrobial peptides. Keywords: Biophysical methods, Nanomedicine, Nanopharmacology, Structure-function relationship.

Bonvin, Nikolay E.

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Abstract: The Antimicrobial peptides e. Content Access Key:. Volume 16 , Issue 1 ,